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More →OpenAI Buys Orchestra Bio to Put AI Agents in Charge of Drug Development Grunt Work
OpenAI has bought Orchestra Bio, a San Francisco startup whose AI agents help drug companies keep sprawling development programs on schedule, the ChatGPT maker <a href="https://openai.com/index/openai-to-acquire-orchestra-bio/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>announced Tuesday</a>. “Our goal is to help scientists make discoveries and manage the work needed to turn them into treatments that reach patients sooner,” OpenAI said in the announcement. Orchestra’s team and platform will be folded into <a href="https://openai.com/rosalind/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>Rosalind</a>, OpenAI’s family of AI models and tools for biologists and chemists. The financial terms were not disclosed. Getting a new medicine from first idea to U.S. approval takes time—up to 15 years according to OpenAI. Every month shaved off that timeline is a month earlier that a new treatment can reach the people waiting for it, and a month earlier that the company can generate cash. The process is also absurdly expensive: bringing one approved drug to market can cost more than <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668846/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>$2.6 billion</a>, and <a href="https://arxiv.org/pdf/2106.05386" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">fewer than 10%</a> of candidates that enter human testing ever make it to pharmacy shelves. Beyond the science itself, OpenAI says drug teams have to coordinate work across internal departments and outside partners, often relying on systems that don’t talk to each other. Those partners usually include contract research organizations, the outside labs hired to run studies, and contract manufacturers that produce the experimental drug. Orchestra’s AI agents—software that can watch over tasks and flag problems on its own—work out which activities and deadlines take the hit, gather the relevant information and compare ways to respond, while scientists and program leaders make the final call. Founded in the fall of 2022, Orchestra raised its <a href="https://jobs.8vc.com/companies/orchestra/jobs/28818089-senior-software-engineer" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>seed round</a> from Andreessen Horowitz, Definition Capital, Insight Partners, and 8VC, and about $20 million in total, according to <a href="https://www.caplight.com/company/orchestra-bio" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">Caplight data</a>. The company should not be confused with Orchestra BioMed, an unrelated Nasdaq-listed medical device maker that trades under the ticker OBIO. In April, OpenAI launched <a href="https://decrypt.co/364783/openai-gpt-rosalind-drug-discovery-life-sciences-model" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">GPT-Rosalind</a>, a model built specifically for biology and dru
Jensen Huang: Market volatility will be resolved, and strong demand is the reason.
According to CoinWorld news, when discussing the impact of AI uncertainty on market volatility, Jensen Huang said: "I think this issue will be resolved, because demand is very strong."
The U.S. Office of the Comptroller of the Currency has completed the development of regulations related to stablecoin rewards under the GENIUS Act.
According to Bijie.com, the U.S. Office of the Comptroller of the Currency is the first federal agency to complete the formulation of regulations related to stablecoin rewards under the GENIUS Act.
Yardeni: The AI bubble is real, but it is not yet ready to burst.
According to CoinWorld news, Yardeni Research's new AI bubble indicator is flashing warnings but not showing crash signals. Bubble conditions stand at 83/100, while crash trigger conditions are only at 34/100. Historically, similar conditions have preceded an S&P 500 bear market only 9% of the time within two years, with a median inflation-adjusted return of 18.3%. The key takeaway: AI valuations look overstretched, but the forces that would burst the bubble have not yet fully materialized.
France proposes amendments to the EU's Markets in Crypto-Assets Regulation.
According to Cointelegraph, the French Treasury, the Financial Markets Authority, the Bank of France, and the Prudential Supervision and Resolution Authority have jointly submitted proposed amendments to the EU's Markets in Crypto-Assets Regulation (MiCA), requiring platforms that provide access to decentralized finance (DeFi) protocols to pre-review those protocols, continuously monitor vulnerabilities and suspicious activity, and bear liability for certain customer losses in cases such as failing to fulfill review obligations or ignoring known security risks. Platforms may still provide access to uncertified protocols after conducting their own due diligence and strengthening risk disclosures, and the related obligations will be adjusted according to the size of the platform. At the same time, France supports transferring regulatory authority over significant crypto-asset service providers to the European Securities and Markets Authority and lowering the current threshold for determining significance.
Iranian Major General Yazdi: Iranian fighter jets are capable of threatening enemy vessels with missiles.
According to CoinWorld news, Iranian Major General Yazdi stated that Iranian fighter jets are capable of threatening enemy vessels with missiles. Iran's missile capabilities have not only increased in quantity but have also made progress in technological level.
Trump will emphasize cracking down on overseas crypto fraud as FBI complaints surge 17%.
Coin World news, according to Reuters, President Trump is preparing to highlight his administration's crackdown on overseas cryptocurrency fraud, as federal agencies target fake investment websites and criminal networks accused of stealing billions of dollars from Americans. Trump and senior cabinet officials are expected to discuss efforts to disrupt foreign scam operations at a cybersecurity event in Washington. The event will focus on criminal organizations that persuade Americans to transfer funds into fake cryptocurrency investments, often through websites designed to look like legitimate trading platforms. Officials are expected to describe the government's seizures of fake investment websites and measures taken against online impersonation schemes. Homeland Security Secretary Markwayne Mullin, FBI Director Kash Patel, Defense Secretary Pete Hegseth, and Attorney General Todd Blanche are among those expected to attend. According to the FBI's 2025 Internet Crime Report, the scale of online fraud continues to grow, with the FBI Internet Crime Complaint Center receiving 1,008,597 complaints in 2025, up from 859,532 in 2024, an increase of about 17%.
AI has entered the practical phase; the past 15 years were in invention mode.
According to a report by Yahoo Finance, a spokesperson stated at the GTC Berlin conference that over the past 15 years, artificial intelligence has been in an "invention mode," but six months ago, AI truly shifted to a "practical mode."
2 consecutive limit-up days for Sunsea AIoT: revenue from innovative high-computing-power module products in the first half of the year accounted for approximately 1% of the company's total revenue.
According to CoinWorld news, [Sunsea AIoT, 2 consecutive limit-up days: revenue from innovative high-computing-power module products in the first half of the year accounted for about 1% of the company's total revenue] Cailian Press, October 21 - Sunsea AIoT (002313.SZ) issued an announcement on abnormal fluctuations in stock trading. The company noted that the market has recently shown high attention to fields such as edge AI and robotics. To avoid misleading investors, it now explains the situation regarding its main products as follows: At present, the structure of the company's main products, such as wireless communication modules, remains stable compared with the previous period, mainly consisting of cellular data transmission modules based on 4G, 5G, NB and other standards, as well as GNSS positioning modules. In the first half of the year, revenue from innovative high-computing-power module products accounted for about 1% of the company's total revenue. In the future, there is a risk that market development for high-end products may fall short of expectations.
EAGLE-4 makes Qwen generation 3.6x faster, and even phone CPUs get a 3x speedup.
According to CoinWorld news, Eagle has released EAGLE-4, an upgrade to its speculative decoding solution that improves Qwen's generation speed. The new version focuses on reducing the computational overhead of the draft model and can adjust the prediction scale based on hardware performance and concurrency levels. On 4 NVIDIA B300 GPUs, the single-request generation speed of Qwen 3.8-27B increased from 240.5 tokens per second to 863.8 tokens per second, a 3.6x improvement; when 512 requests run simultaneously, total throughput increased from 21,200 tokens per second to 28,300, a 34% improvement. There are also notable improvements on mobile devices. On the Motorola Razr 70 Ultra, Gemma-4-E2B-IT achieved a 3.2x increase in long-text generation speed using only the CPU, reducing task time from 43 seconds to 14 seconds and lowering energy consumption per token by 53%. EAGLE-4 has been open-sourced and supports integration with SGLang, VLLM, and the experimental TokenSpeed, but the new version has switched to a restrictive commercial license, and commercial use requires separate authorization.