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More →OpenAI Buys Orchestra Bio to Put AI Agents in Charge of Drug Development Grunt Work
OpenAI has bought Orchestra Bio, a San Francisco startup whose AI agents help drug companies keep sprawling development programs on schedule, the ChatGPT maker <a href="https://openai.com/index/openai-to-acquire-orchestra-bio/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>announced Tuesday</a>. “Our goal is to help scientists make discoveries and manage the work needed to turn them into treatments that reach patients sooner,” OpenAI said in the announcement. Orchestra’s team and platform will be folded into <a href="https://openai.com/rosalind/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>Rosalind</a>, OpenAI’s family of AI models and tools for biologists and chemists. The financial terms were not disclosed. Getting a new medicine from first idea to U.S. approval takes time—up to 15 years according to OpenAI. Every month shaved off that timeline is a month earlier that a new treatment can reach the people waiting for it, and a month earlier that the company can generate cash. The process is also absurdly expensive: bringing one approved drug to market can cost more than <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668846/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>$2.6 billion</a>, and <a href="https://arxiv.org/pdf/2106.05386" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">fewer than 10%</a> of candidates that enter human testing ever make it to pharmacy shelves. Beyond the science itself, OpenAI says drug teams have to coordinate work across internal departments and outside partners, often relying on systems that don’t talk to each other. Those partners usually include contract research organizations, the outside labs hired to run studies, and contract manufacturers that produce the experimental drug. Orchestra’s AI agents—software that can watch over tasks and flag problems on its own—work out which activities and deadlines take the hit, gather the relevant information and compare ways to respond, while scientists and program leaders make the final call. Founded in the fall of 2022, Orchestra raised its <a href="https://jobs.8vc.com/companies/orchestra/jobs/28818089-senior-software-engineer" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>seed round</a> from Andreessen Horowitz, Definition Capital, Insight Partners, and 8VC, and about $20 million in total, according to <a href="https://www.caplight.com/company/orchestra-bio" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">Caplight data</a>. The company should not be confused with Orchestra BioMed, an unrelated Nasdaq-listed medical device maker that trades under the ticker OBIO. In April, OpenAI launched <a href="https://decrypt.co/364783/openai-gpt-rosalind-drug-discovery-life-sciences-model" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">GPT-Rosalind</a>, a model built specifically for biology and dru
BTC large holder account long-short ratio is 1.1654
CoinWorld data: The latest 4-hour snapshot of BTCUSDT shows that among the top 20% of accounts by margin balance, the long-to-short account ratio is 1.1654, with more net long accounts among large holders. Compared with the same-metric snapshot 24 hours ago, it is down 0.4822; compared with the same-metric snapshot 7 days ago, it is down 0.5668.
Saudi Ministry of Energy: Air defense forces intercepted a drone attack on Saudi Aramco's Shaybah oil field.
Saudi Arabia's Ministry of Energy stated that air defense forces successfully intercepted a drone attempting to attack Saudi Aramco's Shaybah oil field facilities. Following the drone attack, operations at Saudi Aramco's Shaybah oil field were unaffected.
Spot silver fell to $57/oz, down 1.74% intraday.
According to CoinWorld news, spot silver fell to $57 per ounce, down 1.74% intraday. Spot gold moved lower within 15 minutes and is now at $4,107 per ounce. In addition, reports say the U.S. State Department is preparing to order the evacuation of some personnel and family members from U.S. embassies in the Gulf region.
Coinbase Derivatives will undergo maintenance on October 24.
Coinbase has announced that its derivatives will undergo scheduled maintenance on Saturday, October 24, at 5:00 AM (CT), expected to last 9 hours. During the maintenance period, futures and perpetual futures trading on Coinbase Financial Markets will be unavailable, but account access will remain unchanged.
NSA warns of critical cybersecurity vulnerabilities involving AI
According to CoinWorld news, the NSA (U.S. National Security Agency) has warned that critical cybersecurity vulnerabilities exploiting AI technology have been discovered. These vulnerabilities could pose a threat to national security, and relevant departments are actively responding.
Alex Gluchowski: Bank blockchain projects struggle to move from pilot to production environment
Matter Labs CEO Alex Gluchowski said that although most banks have tested blockchain technology, very few have put it into production. Technology is not the main obstacle; the core issue lies in infrastructure. He also introduced the Prividium Commander product.
The United States plans to order the evacuation of some embassy personnel in the Gulf region.
BiJie Network News, according to Reuters, the U.S. State Department is preparing to order the evacuation of some U.S. embassy staff and their families in the Gulf region. Two officials said the move is due to the possible resumption of hostilities, especially the possibility of renewed conflict with the Iran-aligned Houthi militants in Yemen.
SpaceX's Q3 earnings beat expectations, pushing Bitcoin up to $84,600.
CoinWorld data: According to Cointelegraph, SpaceX's third-quarter earnings exceeded expectations, boosting market risk sentiment, and Bitcoin's price rose to $84,600. Bitcoin's gains synchronized with the U.S. stock market, and the positive market reaction to the earnings brought Bitcoin back close to the $85,000 level.
Kuwait Petroleum Corporation CEO: Daily production exceeds 2 million barrels.
Sheikh Nawaf Saud Al-Nasser Al-Sabah, CEO of Kuwait Petroleum Corporation, said the company has maintained crude oil deliveries at pre-conflict levels through the use of alternative shipping arrangements and strategic tankers, with daily production exceeding 2 million barrels.