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More →OpenAI Buys Orchestra Bio to Put AI Agents in Charge of Drug Development Grunt Work
OpenAI has bought Orchestra Bio, a San Francisco startup whose AI agents help drug companies keep sprawling development programs on schedule, the ChatGPT maker <a href="https://openai.com/index/openai-to-acquire-orchestra-bio/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>announced Tuesday</a>. “Our goal is to help scientists make discoveries and manage the work needed to turn them into treatments that reach patients sooner,” OpenAI said in the announcement. Orchestra’s team and platform will be folded into <a href="https://openai.com/rosalind/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>Rosalind</a>, OpenAI’s family of AI models and tools for biologists and chemists. The financial terms were not disclosed. Getting a new medicine from first idea to U.S. approval takes time—up to 15 years according to OpenAI. Every month shaved off that timeline is a month earlier that a new treatment can reach the people waiting for it, and a month earlier that the company can generate cash. The process is also absurdly expensive: bringing one approved drug to market can cost more than <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668846/" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>$2.6 billion</a>, and <a href="https://arxiv.org/pdf/2106.05386" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">fewer than 10%</a> of candidates that enter human testing ever make it to pharmacy shelves. Beyond the science itself, OpenAI says drug teams have to coordinate work across internal departments and outside partners, often relying on systems that don’t talk to each other. Those partners usually include contract research organizations, the outside labs hired to run studies, and contract manufacturers that produce the experimental drug. Orchestra’s AI agents—software that can watch over tasks and flag problems on its own—work out which activities and deadlines take the hit, gather the relevant information and compare ways to respond, while scientists and program leaders make the final call. Founded in the fall of 2022, Orchestra raised its <a href="https://jobs.8vc.com/companies/orchestra/jobs/28818089-senior-software-engineer" target="_blank" rel="nofollow external noopener" class="sc-adb616fe-0 dJryYS">>seed round</a> from Andreessen Horowitz, Definition Capital, Insight Partners, and 8VC, and about $20 million in total, according to <a href="https://www.caplight.com/company/orchestra-bio" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">Caplight data</a>. The company should not be confused with Orchestra BioMed, an unrelated Nasdaq-listed medical device maker that trades under the ticker OBIO. In April, OpenAI launched <a href="https://decrypt.co/364783/openai-gpt-rosalind-drug-discovery-life-sciences-model" target="_blank" class="sc-adb616fe-0 dJryYS" rel="nofollow">GPT-Rosalind</a>, a model built specifically for biology and dru
Grayscale launches a digital asset in-kind investment service, allowing direct exchange of digital assets for product shares.
CoinWorld news: Grayscale has announced the launch of an in-kind digital asset investment service, allowing eligible investors to exchange digital assets directly for shares in Grayscale products without first converting cryptocurrency into cash. The service currently covers 10 products, involving BTC, ETH, SOL, AVAX, LINK, DOGE, HYPE, SUI, XRP, and ZEC. Grayscale stated that this mechanism helps reduce the burden of self-custody and potential transaction costs for investors, and incorporates digital assets into traditional portfolio management.
Tether leads the seed funding round for Bolivian fintech company Peso.
CoinWorld news, Tether announced that it led the pre-seed funding round of Bolivian fintech company Peso. The funds will be used to expand local fiat on-ramp and off-ramp channels in Bolivia, Brazil, Colombia, and Argentina, and to advance the construction of a merchant payment collection network and virtual account infrastructure. Peso offers USDT accounts that support savings, spending, investment, and cross-border transfers. It has already integrated USDT food delivery payments on the Bolivian digital services platform Yango, and connects to the local banking system through QR codes and an automated clearing system. The funding amount was not disclosed.
OpenAI has partnered with PerturbAI and Scripps Research to analyze brain cell data.
OpenAI announced a collaboration with PerturbAI and Scripps Research, using thousands of GPT-Rosalind-based AI agents to analyze experimental data from millions of mouse brain cells within 32 minutes, identifying potential associations between genetic perturbations and cellular responses, and combining scientific literature to propose new research leads. OpenAI said that if humans were to carry out the same scale of analysis and literature review item by item, it would be expected to take months to a year. In blind comparison tests, human experts preferred the reports generated by multiple agents over single-agent reports in 75% of cases. The research also proposed a potential link between cholesterol regulation and neurodegenerative diseases, and the related hypothesis still requires subsequent experimental validation.
Banzai International: The company will repurchase 1.7 million warrants for $1.5 million.
Banzai International has filed with the SEC to repurchase 1.7 million warrants for $1.5 million, according to Reuters.
OCC issues final GENIUS Act rules: rewards allowed but no guarantee
CoinWorld news, the OCC (Office of the Comptroller of the Currency) on Wednesday released its first comprehensive GENIUS Act rule, allowing certain stablecoin rewards but not guaranteeing them. The OCC removed the presumption that certain affiliate and third-party stablecoin rewards violate the legal prohibition on issuers paying interest. The rule will take effect on January 18, 2027, and the OCC said each reward arrangement will be evaluated based on its economics. Despite industry opposition to the rule, the final rule accepted some industry views and removed the presumption, but the prohibition clause remains. The OCC also said existing programs do not have to be shut down before the new law takes effect, and each program does not require formal approval.
Tokenized assets in lending markets reach $64 million in lending volume.
CoinWorld data: According to Messari, over the past month, the borrowing scale of tokenized assets in the lending market reached $64 million, hitting an all-time high and representing a more than 10-fold increase compared to last month.
Tether invests in peso to expand USDT payment infrastructure in Latin America
CoinWorld data: Tether has announced an investment in the peso to expand its USDT payment infrastructure in Latin America. This move aims to enhance payment convenience in the region and further promote the adoption of stablecoins.
OpenAI expands ChatGPT ads business to 26 new countries and regions.
CoinWorld news, OpenAI announced a further expansion of its ChatGPT advertising business, adding 26 new countries and regions. The company said that more than 100,000 advertisers have already used the platform, and ChatGPT ads now cover 89 countries and regions worldwide. The newly added markets include 14 countries in Latin America, as well as multiple markets in Europe, the Middle East, Africa, and Asia. Ads are currently shown only to users of the free and Go versions, while Plus, Pro, and Enterprise subscriptions still do not display ads. OpenAI stated that ads will be clearly labeled and kept separate from ChatGPT answers, and that ads will not affect the content of responses.
Peso完成Pre-Seed轮融资，Tether领投
Cointime news: Bolivian fintech company Peso has completed a Pre-Seed funding round led by Tether. The funds will be used to expand local fiat on-ramp and off-ramp channels in Bolivia, Brazil, Colombia, and Argentina, and to build a merchant POS payment network and virtual account infrastructure.